Qalabka Ogaanshaha Aspergillus Galactomannan ELISA
Hordhac Product
FungiXpert® Aspergillus Galactomannan ELISA Detection Kit waa shaybaar immunosorbent ku xidhan Enzyme oo loogu talagalay ogaanshaha tayada ee Aspergillus galactomannan antigen ee dadka qaangaarka ah iyo muunadaha serum ee carruurta iyo shaybaarada dareeraha ee bronchoalveolar lavage (BAL).
Dhacdooyinka Aspergillosis ee Invasive (IA) ee bukaannada difaaca jirka ayaa si degdeg ah u kordhaya sababtoo ah xadgudubka antibiyootiga.IA waxay leedahay heer dhimasho sare leh sababtoo ah la'aanta muuqaalada caafimaad ee caadiga ah iyo hababka ogaanshaha hore ee waxtarka leh.Aspergillus fumigatus waa mid ka mid ah cudurada ugu badan ee keena caabuqa aspergillus daran ee bukaanka qaba cudurrada difaaca jirka, waxaana ku xiga Aspergillus flavus, Aspergillus niger iyo Aspergillus terreus.
Astaamaha
| Magaca | Qalabka Ogaanshaha Aspergillus Galactomannan ELISA |
| Habka | ELISA |
| Tusaalaha nooca | Serum, dareeraha BAL |
| Tilmaamid | 96 tijaabo/xirmo |
| Waqtiga ogaanshaha | 2 h |
| Walxaha la ogaado | Aspergillus spp. |
| Xasilooni | Qalabku wuxuu xasilan yahay 1 sano oo ah 2-8 ° C |
| Xadka ogaanshaha hooseeya | 0.5 ng/ml |
Asalkii hore
Aspergillosis invasive (IA)
Yaa u nugul
Bukaanka qaba neutropenia daba dheeraatay, ka dib tallaalka ama iyadoo lala kaashanayo hababka difaaca jirka ee xoogga leh.
Dhacdo sare
5% ilaa 20%, taas oo ku xidhan dadka bukaanka ah.
Heerka dhimashada sare
50% ilaa 80% sababtoo ah qayb ahaan horumarka degdega ah ee caabuqa (ie, 1-2 toddobaad laga bilaabo bilawga ilaa dhimashada).
Way adag tahay in la ogaado
Way adag tahay in la helo caddaynta histopathological.Dareenka dhaqanku wuu hooseeyaa.≈30% kiisaska ayaa ah kuwo aan la baarin oo aan la daweyn marka ay dhintaan.
Imtixaanka Galactomannan (GM).
- Aspergillus antigen gaar ah oo laga helay gidaarka unugga kaas oo la sii daayo inta lagu jiro marxaladda koritaanka ee aspergillosis invasive.
- 7 ilaa 14 maalmood ka hor inta aanay muuqan calaamado kale oo ogaanshaha.
Mabda'a
Faa'iidooyinka
- Hormarin badan
Habka ogaanshaha cirifka sare ee caalamiga ah, dareen sare iyo gaar ahaaneed - Sax badan
Wanaaji habka hawlgalkaIska yaree khatarta wasakhowga inta lagu jiro tijaabada - Degdeg ah
Ogaanshaha hal-tallaabo, dhimista tirada soo-jiidashada iyo wakhtiga dhaqidda
- Dhaqaale badan
Kala qaybsan microplate, kaydinta kharashka - Talooyin
Waxaa lagu taliyay IDSA tilmaanta Aspergillosis 2016 iyo ESCMID-ECMM-ERS tilmaamta Aspergillosis 2018
Saamaynta caafimaad
Hore u ogaanshaha
- GM waa 5-8 maalmood ka hor calaamadaha kiliinikada ee aspergillosis invasive (IA);
- GM waa 7.2 maalmood ka hor sawirka sare ee CT;
- GM waa 12.5 maalmood ka hor bilowga daawaynta antifungal ee la taaban karo.
la socodka firfircoon
- GM waxay u dhigantaa qadarka fungus, taas oo ka tarjumaysa heerka caabuqa.
- Waxyaabaha ku jira antigen-ka GM ayaa hoos u dhacay isticmaalka daawooyinka antifungal.
Saldhig caafimaad oo muhiim ah
- Iska yaree isticmaalka daawaynta ka hortagga fangas ee la taaban karo.
- Xidhiidh adag oo u dhexeeya natiijada iyo index GM ee kansarka dhiigga.
Ogaanshaha United ee G iyo GM test
- Gaar ahaan sare iyo qiimaha saadaaliyaha togan
- Dareenka sare
Macluumaadka Dalabka
| Qaabka | Sharaxaada | Koodhka badeecada |
| GMKT-01 | 96 tijaabo/xirmo | FGM096-001 |
