OXA-48 OXA-48 Ogaanshaha U adkaysiga Carbapenem
Hordhac Product
OXA-48 OXA-48 Ogaanshaha OXA-48 Ogaanshaha K-Set (Lateral Flow Assay) waa nidaam tijaabo ah oo immunochromatographic ah oo loogu talagalay in lagu ogaado tayada OXA-48-carbapenemase-nooca carbapenemase ee deegaannada bakteeriyada.Imtixaanku waa shaybaadhka isticmaalka rijeetada kaas oo ka caawin kara ogaanshaha noocyada OXA-48 ee carbapenem u adkaysta.
Astaamaha
| Magaca | OXA-48 OXA-48 Ogaanshaha U adkaysiga Carbapenem |
| Habka | Baaritaanka socodka dambe |
| Tusaalaha nooca | Gumeysiga bakteeriyada |
| Tilmaamid | 25 tijaabo/xirmo |
| Waqtiga ogaanshaha | 10-15 daqiiqo |
| Walxaha la ogaado | Enterobacteriaceae (CRE) u adkaysta Carbapenem |
| Nooca ogaanshaha | OXA-48 |
| Xasilooni | K-Set-ku wuu xasiloon yahay 2 sano marka uu joogo 2°C-30°C |
Faa'iidada
- Degdeg ah
Ku hel natiijada 15 daqiiqo gudahood, 3 maalmood ka hor hababka ogaanshaha dhaqameed - SOXA-48le
Si fudud loo isticmaalo, shaqaalaha shaybaadhka caadiga ah waxay shaqayn karaan tababar la'aan - Sax ah
Dareen sare iyo gaar ahaaneed
Xadka ogaanshaha hooseeya: 0.10 ng/ml
Awood u leh inuu ogaado badi noocyada hoose ee caadiga ah ee OXA-48
- Natiijo dareen leh
Looma baahna xisaabin, natiijada akhriska muuqaalka ah - Dhaqaale
Alaabta waa la rari karaa laguna kaydin karaa heerkulka qolka, hoos u dhigista kharashyada
Muhiimadda imtixaanka CRE
CRE, oo u taagan carbapenem u adkaysta Enterobacteriaceae, waa qoys jeermis ah oo ay adag tahay in la daweeyo sababtoo ah waxay aad ugu adkeysanayaan antibiyootiga.Noocyada Klebsiella iyo Escherichia coli (E. coli) waa tusaaleyaal Enterobacteriaceae, oo ah qayb caadi ah oo ka mid ah bakteeriyada xiidmaha bini'aadamka oo noqon karta mid u adkaysata carbapenem.Sababta ay CRE-yadu u adkeysan karaan carbapenems waa sababtoo ah waxay soo saaraan carbapenemases.
Dhakhaatiirtu waxay door muhiim ah ka ciyaaraan yaraynta fiditaanka CRE.Caadi ahaan, waxay kaa caawin karaan ka hortagga faafitaanka CRE by
- Ogow haddii bukaannada qaba CRE la dhigo isbitaal ama loo wareejiyo xarunta, oo la soco heerarka caabuqa CRE.
- Dhig bukaanka hadda ama hore loo gumaystay ama cudurka CRE ku dhacay Taxaddarrada Xiriirka.
- Hubi in shaybaaradu ay isla markiiba u digaan shaqaalaha caafimaadka iyo ka hortagga caabuqa marka CRE la aqoonsado
- Si xikmad leh u qor oo u isticmaal antibiyootiga
- Jooji aaladaha wax soo weerara sida ugu dhaqsaha badan marka aan loo baahnayn
……
In si degdeg ah loo aqoonsado bukaanada la gumaysto ama cudurka qaba noolahaan oo la geliyo Taxadirka Xiriirka marka ay habboon tahay, iyadoo la isticmaalayo antibiyootiga si xikmad leh, iyo yareynta isticmaalka aaladaha ayaa dhamaantood ah qaybo muhiim ah oo ka hortagga gudbinta CRE, taas oo macnaheedu yahay in si degdeg ah oo sax ah loo ogaado CRE waa mid aad lagama maarmaan u ah.
OXA-48-tye carbapenemase
Carbapenemase waxaa loola jeedaa nooc ka mid ah β-lactamase kaas oo ugu yaraan si weyn u hydrolyze imipenem ama meropenem, oo ay ku jiraan A, B, D saddex nooc oo ensaymes ah oo lagu kala saaro qaabka molecular Ambler.Fasalka D, sida nooca OXA-carbapenemase, ayaa inta badan laga helay Acinetobacteria.Daraasadaha la-socodku waxay muujiyeen in nooca OXA-48-carbapenemases, oo sidoo kale loo yaqaan oxacillinase-48-like beta-lactamase, ay yihiin carbapenemases-ka ugu badan ee Enterobacterales ee gobollada qaar ee adduunka waxaana si joogto ah loogu soo bandhigaa gobollada aan caadiga ahayn, halkaas oo ay masuul ka yihiin dillaaca isbitaallada.
Hawlgalka
- Ku dar 5 dhibcood oo muunad daawaynta ah
- Ku daadi xayndaabyada bakteeriyada xayndaabka tallaalka la tuuri karo
- Geli wareegga tuubada
- Ku dar 50 μL si fiican S, sug 10-15 daqiiqo
- Akhri natiijada
Macluumaadka Dalabka
| Qaabka | Sharaxaada | Koodhka badeecada |
| CPO48-01 | 25 tijaabo/xirmo | CPO48-01 |
