OXA-23 OXA-23 Ogaanshaha U adkaysiga Carbapenem
Hordhac Product
OXA-23 Ogaanshaha OXA-23 ee Carbapenem u adkaysta K-Set (Lateral Flow Assay) waa nidaam tijaabo ah oo immunochromatographic ah oo loogu talagalay in lagu ogaado tayada OXA-23-carbapenemase-nooca carbapenemase ee deegaannada bakteeriyada.Baaritaanku waa shaybaar la isticmaalo rijeeto oo ka caawin kara ogaanshaha noocyada OXA-23 ee carbapenem u adkaysta.
Astaamaha
| Magaca | OXA-23 OXA-23 Ogaanshaha U adkaysiga Carbapenem |
| Habka | Baaritaanka socodka dambe |
| Tusaalaha nooca | Gumeysiga bakteeriyada |
| Tilmaamid | 25 tijaabo/xirmo |
| Waqtiga ogaanshaha | 10-15 daqiiqo |
| Walxaha la ogaado | Enterobacteriaceae (CRE) u adkaysta Carbapenem |
| Nooca ogaanshaha | OXA-23 |
| Xasilooni | K-Set-ku wuu xasiloon yahay 2 sano marka uu joogo 2°C-30°C |
Faa'iidada
- Degdeg ah
Ku hel natiijada 15 daqiiqo gudahood, 3 maalmood ka hor hababka ogaanshaha dhaqameed - SOXA-23le
Si fudud loo isticmaalo, shaqaalaha shaybaadhka caadiga ah waxay shaqayn karaan tababar la'aan - Sax ah
Dareen sare iyo gaar ahaaneed
Xadka ogaanshaha hooseeya: 0.10 ng/ml
Awood u leh inuu ogaado badi noocyada hoose ee caadiga ah ee OXA-23
- Natiijo dareen leh
Looma baahna xisaabin, natiijada akhriska muuqaalka ah - Dhaqaale
Alaabta waa la rari karaa laguna kaydin karaa heerkulka qolka, hoos u dhigista kharashyada
Muhiimadda imtixaanka CRE
CRE (Carbapenem u adkaysta Enterobacteriaceae) waa qoys jeermis ah oo ay adag tahay in la daweeyo sababtoo ah waxay aad ugu adkaysanayaan antibiyootiga.Caadi ahaan infekshannada CRE waxay ku dhacaan bukaannada isbitaallada, guryaha dadka lagu xanaaneeyo, iyo goobaha kale ee daryeelka caafimaadka.Bukaannada daryeelkoodu u baahan yahay aaladaha sida hawo-mareenada (mashiinnada neefsashada), tuubbooyinka kaadi-haysta (kaadi-haysta), tuubooyinka xididdada (xididka), iyo bukaannada qaadanaya koorasyada dheer ee antibiyootiga qaarkood waxay halis ugu jiraan caabuqyada CRE.
Bakteeriyada CRE qaarkood ayaa iska caabisay inta badan antibiyootiga la heli karo.Caabuqa jeermiskan ayaa ah mid aad u adag in la daweeyo, waxayna noqon karaan kuwo dilaa ah—hal warbixin ayaa sheegaysa inay gacan ka geysan karaan dhimashada ilaa 50% bukaanada qaaday cudurka.
Si looga hortago fiditaanka CRE, daryeelka caafimaadku waa inuu bixiyaa
- La soco heerarka caabuqa CRE.Weydii haddii bukaan uu helay daryeel caafimaad meel kale, oo uu ku jiro waddan kale.
- Dhig bukaanada uu ku dhacay CRE Taxaddarrada Xiriirka.Go'doon waa lama huraan.
- Samee nadaafadda gacmaha - isticmaal gacmaha oo alkohol ku xoq ama ku dhaq saabuun iyo biyo ka hor iyo ka dib markaad la xiriirto bukaanka ama deegaankooda
- U fiirso xarunta qaabilaadda marka aad wareejinayso bukaan CRE, oo ogow marka bukaan CRE uu ku wareejiyo xaruntaada
- Hubi in shaybaaradu ay isla markiiba u digaan shaqaalaha caafimaadka iyo ka hortagga caabuqa marka CRE la aqoonsado
- Si xikmad leh u qor oo u isticmaal antibiyootiga
- Jooji qalabka sida kateetarka kaadi mareenka isla markaaba marka aan loo baahnayn
……
Si degdeg ah loo aqoonsado bukaanada qaba CRE iyo ka soocida bukaanada kale ee ICU marka ay habboon tahay, isticmaalka antibiyootiga si macquul ah, iyo yaraynta isticmaalka qalabka wax soo saarka ayaa muhiim u ah ka hortagga gudbinta CRE.Tijaabada degdega ah ee CRE waa shardi lagama maarmaan u ah hirgelinta hababkan, taas oo ka dhigaysa qayb muhiim ah oo ka mid ah maareynta CRE ee bukaan-socodka.
OXA-23-nooca carbapenemase
Carbapenemase waxaa loola jeedaa nooc ka mid ah β-lactamase kaas oo ugu yaraan si weyn u hydrolyze imipenem ama meropenem, oo ay ku jiraan A, B, D saddex nooc oo ensaymes ah oo lagu kala saaro qaabka molecular Ambler.Fasalka D, sida nooca OXA-carbapenemase, ayaa inta badan laga helay Acinetobacteria.Sanadihii la soo dhaafay, waxaa jiray warbixino ku saabsan isbitaal dhigashada ay sababtay OXA-23, ie Oxacillinase-23-like beta-lactamase.80% ee carbapenem u adkaysta Acinetobacteria baumannii waxay soo saartaa nooca OXA-23 carbapenemase, taas oo ka dhigaysa daaweynta kiliinikada mid aad u adag.
Hawlgalka
- Ku dar 5 dhibcood oo muunad daawaynta ah
- Ku daadi xayndaabyada bakteeriyada xayndaabka tallaalka la tuuri karo
- Geli wareegga tuubada
- Ku dar 50 μL si fiican S, sug 10-15 daqiiqo
- Akhri natiijada
Macluumaadka Dalabka
| Qaabka | Sharaxaada | Koodhka badeecada |
| CPO23-01 | 25 tijaabo/xirmo | CPO23-01 |
